Doses of 300 mg or less can be taken as a single daily dose, but higher doses should be split up into a few smaller doses per day. The recommended dose for preventing calcium oxalate kidney stones is 200 mg or 300 mg per day, taken as a single dose. Never take more than the prescribed dose. Precautions Before taking Allopurinol you should talk with your doctor if you have liver failure, cirrhosis, or hepatitis, kidney failure, allergies to foods, dyes, or preservatives, if you are pregnant or thinking of becoming pregnant and breastfeeding. You should stop taking Allopurinol immediately and contact your doctor if you develop a rash. Sometimes, a rash is the first sign of dangerous reactions to Allopurinol, such as Stevens-Johnson syndrome, liver damage, or even death.

Allopurinol can cause drowsiness. So avoid driving. It is important to drink plenty of fluids, in order to help prevent kidney stones from forming. Contraindications You shouldn't use Allopurinol if you have hypersensitivity to the drug, renal impairment, hepatic impairment, acute attack of gout. It is not recommended in children under 14 years of age. Possible side effect Seek emergency medical help if any of these side effects occur: If you have questions about side effects, contact your doctor for medical advice. Drug interactions Allopurinol can potentially interact with: ACE inhibitors Quinapril, Enalapril, Ramipril , ampicillin, antacids, cyclophosphamide, diuretics Ethacrynic acid, Furosemide, Chlorothiazide , warfarin.

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