As already mentioned, one of the most common side effects is stomach upset, which can include abdominal pain, diarrhea, nausea or vomiting. Patients are usually advised to take the medicine with food, as this can help reduce these symptoms. Although rare, some people who use this drug will develop other side effects, which may include rash, disorientation, headache, mood changes, hallucinations, dry mouth, and an unpleasant or metallic taste in the mouth. These symptoms should be given to the doctor, as well as any other symptoms that reduce urination or cause jaundice jaundice of the skin and eye proteins. Since Biaxin Clarithromycin is cleared through the liver, in very rare cases it may be associated with liver damage.
To avoid more serious side effects, patients should discuss with doctors what medications they are currently taking, including dietary supplements or herbs. They should also provide what medical conditions they have. Many people do not have negative reactions to this drug, and the antibiotic Biaxin can effectively treat them. In what cases should not take Biaxin? Before taking Biaxin, tell your doctor if you have kidney or liver disease. It may require a reduced dose and monitoring throughout the course of treatment, or withdrawal of the drug.
Biaxin is classified as category C by the FDA in relation to pregnancy. This means that it is not known whether the drug can adversely affect the fetus. If you are pregnant, do not take biaxin without consulting a doctor. It is unknown whether the biaxin is able to penetrate into breast milk. If you are a nursing mother, do not take this drug without consulting your doctor. Method of application Biaxin should be taken, clearly following the instructions of the doctor. Consult your doctor or pharmacist for directions on use. Each dose should be washed down with a full glass of water 200 milliliters.
Biaxin can be taken with food, milk or on an empty stomach. A variety of long-acting biaxin Biaxin XL should be taken with food. As a rule, biaxin is taken twice a day at intervals of 12 hours. Follow the doctor's instructions. Shake before use. For proper dosing, use a measuring spoon, pipette or glass. Ask your pharmacist where you can buy measuring utensils, if you do not have one. Take Biaxin Clarithromycin should be within the period prescribed by your doctor, even if your health has improved. The improvement may be to completely get rid of the infection.
Store the medicine at room temperature in a cool, dry place. Do not keep the suspension in the refrigerator. What happens if i miss a dose? Take your medicine as soon as you think about it. If already approaching the time of the next dose, do not take the missed dose. You should wait for the next dose. Do not take a double dose Biaxin unless directed by your doctor. What happens in case of Biaxin overdose? Seek medical advice immediately. Symptoms of biaxin overdose include nausea, vomiting, diarrhea, abdominal cramps. Precautionary measures Do not start taking Clarithromycin Biaxin if you are taking Cisapride, Pimozide or Terfenadine. These drugs can interact, which can cause a dangerous heart rate failure.
What are the possible side effects? In case of any of the following serious side effects, stop taking the drug Biaxin immediately and consult a doctor: Allergic reaction difficulty breathing; narrowing of the respiratory tract; swelling of the lips, tongue, face or rash ; Liver damage yellowing of the skin or eye proteins, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue. More likely to occur other, less serious side effects. Continue taking the drug Biaxine and tell your doctor if you have any: Nausea, vomiting, diarrhea or abdominal pain; Dizziness, fatigue or headache; A rash; Vaginal thrush. Other side effects not described in this manual may occur.
Any unusual side effects, especially those that cause your concern, should be reported to your doctor. How effective is it in the treatment of common diseases? The use of Biaxin in pneumonia is justified if pneumonia is caused by intracellular bacteria. We are talking about atypical pneumonia, which occurs under the influence of chlamydia or Mycoplasma. Atypical pneumonia, often leading to pulmonary heart failure, can also occur as a result of the reproduction of Legionella. Use this medicine for the full prescribed length of time, even if your symptoms quickly improve.
Skipping doses can increase your risk of infection that is resistant to medication. Store this medicine in the original container at room temperature, away from moisture, heat, and light. If your infection is treated with a combination of drugs, use all medications as directed by your doctor. Read the instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. See also: Biaxin dosage information in more detail What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose.
Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include severe stomach pain , nausea , vomiting , or diarrhea. What should I avoid while taking Biaxin? Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to. Biaxin side effects Get emergency medical help if you have signs of an allergic reaction to Biaxin: Call your doctor at once if you have: If you've ever had heart problems, clarithromycin may cause a heart attack or stroke years after you've taken this medicine.
Seek medical attention right away if you have chest pain spreading to your jaw or shoulder, trouble breathing, slurred speech, or sudden numbness or weakness on one side of your body. Older adults may be more likely to have heart rhythm side effects, including a life-threatening fast heart rate. Common Biaxin side effects may include: This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Biaxin side effects in more detail What other drugs will affect Biaxin?
When you start or stop taking Biaxin, your doctor may need to adjust the doses of any other medicines you take on a regular basis. Many drugs can interact with clarithromycin, and some drugs should not be used together. This includes prescription and over-the-counter medicines, vitamins , and herbal products.
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1/16/ · Buy Biaxin Online With Low Price. Support Drug Guide: purchase the best generic medicine from our sponsor, online pharmacy store, where you can place an order and buy generic Biaxin online over the counter at lowest prices, worldwide delivery. Prices for Biaxin (Clarithromycin) according to the dosage forms and number of pills.4/5(1). Biaxin XL Filmtab (clarithromycin extended-release tablet computers) are shown for the treatment of grownups with moderate to mild infection caused by vulnerable strains of the designated microbes in the problems listed here. Biaxin XL mg. Biaxin XL. There is a danger of serious hemorrhage and substantial altitudes in INR and prothrombin time when clarithromycin is co-administered with warfarin. INR and also prothrombin times ought to be frequently checked while individuals are getting clarithromycin and also oral anticoagulants concurrently.
Drug-Drug Interactions Antifungal imidazoles In three patients with pulmonary MAC and aspergillosis infections, itraconazole was suggested to increase the plasma concentration of clarithromycin as well as the clarithromycin: This effect may have been due to inhibition of CYP3A4 by itraconazole. Antihistamines Toxic effects of terfenadine and astemizole have been reported in patients taking concomitant macrolides, especially clarithromycin, typically resulting in prolongation of the QT interval and cardiac dysrhythmias torsade de pointes. Cisapride Cisapride can prolong the QT interval, with a risk of ventricular dysrhythmias. Clarithromycin increases serum concentrations of cisapride.
This potentially dangerous interaction can result in QT interval prolongation and dysrhythmias such as torsade de pointes. Torsade de pointes occurred in a 77-year-old woman taking cisapride and clarithromycin. Warnings have been issued by the manufacturers to avoid concomitant administration. Colchicine Fatal colchicine intoxication occurred in a 67-year-old man who had taken clarithromycin 500 mg bd for 4 days. Clarithromycin may have inhibited colchicine metabolism and caused a rise in colchicine concentration. Digoxin Clarithromycin has been reported to cause digoxin toxicity.
Two different mechanisms are involved, inhibition of the renal excretion of digoxin and alteration of intestinal flora, which reduces the presystemic hydrolysis of digoxin. A 70-year-old woman taking digoxin for atrial fibrillation developed nausea, vomiting, and dizziness 2 days after starting to take clarithromycin. Her serum digoxin concentration was 3. Disulfiram Fatal toxic epidermal necrolysis and fulminant hepatitis occurred shortly after the start of treatment with clarithromycin in a 47-year-old man who was taking disulfiram. He then took clarithromycin 500 mg bd and paracetamol 500 mg tds and 1 week later noticed non-pruritic cutaneous macu-lopapular lesions on his legs, extending to the rest of his body, excluding the palms and soles.
Previous drug therapy was withdrawn. A skin biopsy showed toxic epidermal necrolysis. During the next several days the skin lesions worsened. He developed septic shock and, despite supportive measures, died. Ergot alkaloids In patients with ergotamine toxicity, vasoconstriction can lead to frank ischemia. Clarithromycin interferes with ergotamine metabolism. A 41-year-old woman developed worsening lower leg pain, pallor, and a sensation of coolness aggravated by exertion; there was severe vasospasm in the legs. However, if the two drugs were taken at least 2 hours apart, the pharmacokinetics of zidovudine were unaffected. In 12 HIV-positive patients there was no statistically significant difference in concentrations of didanosine when clarithromycin was added.
In contrast, there was no change with azithromycin, suggesting that it is much safer for co-administration with midazolam. Pimozide Clarithromycin inhibits the metabolism of pimozide, pimozide plasma concentrations increase, and there is an increased risk of cardiotoxicity through prolongation of the QT interval and fatal ventricular dysrhythmias. Rifamycins Clarithromycin is one of the core drugs for Mycobacterium avium complex infections in both HIV-infected and non-infected patients. The interaction of clarithromycin with the rifamycins is complex.
The changes in serum concentrations of clarithromycin and its metabolite in the presence of the enzyme inducers rifampicin and rifabutin suggest that metabolism of clarithromycin by CYP3A4 is increased. After the addition of rifampicin, peak serum concentrations of clarithromycin fell markedly, from a mean of 5. At the same time the ratio of the serum concentrations of clarithromycin and its 14-OH metabolite was reversed from 3. Whether these changes in serum clarithromycin concentrations are relevant to its antimicrobial activity is unknown, since prediction of clinical efficacy based on serum concentrations of clarithromycin is probably not justified, given that the macrolides accumulate to a large degree in tissues and macrophages.
The effects of fluconazole and clarithromycin on the pharmacokinetics of rifabutin and 25-O-desacetylrifabu-tin have been studied in ten HIV-infected patients who were given rifabutin 300 mg qds in addition to fluconazole 200 mg qds and clarithromycin 500 mg qds. The authors concluded that patients should be monitored for adverse effects of rifabutin when it is co-administered with fluconazole or clarithromycin. Both developed severe hypoglycemia within 48 hours of starting clarithromycin. Tacrolimus Clarithromycin can increase the steady-state concentrations of drugs that depend primarily on CYP3A metabolism.
Steady-state tacrolimus concentrations rose in a 32-year-old African-American man who took clarithromycin 500 mg bd for 4 days. In two women aged 37 and 69, acute and reversible tacrolimus nephrotoxicity developed after the addition of clarithromycin for an upper respiratory tract infection. Theophylline and other xanthines Inhibition of cytochrome P450 activity by clarithromycin affects the metabolism of theophylline. However, the results of several studies of the effect of clarithromycin on theophylline concentrations are conflicting. How should I take Biaxin?
Take Biaxin exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Do not use clarithromycin to treat any condition that has not been checked by your doctor. Do not share this medicine with another person, even if they have the same symptoms you have. You may take the regular tablets with or without food. Biaxin XL extended-release tablets should be taken with food. Do not crush, chew, or break an extended-release tablet.
Swallow it whole. Use this medicine for the full prescribed length of time. Biaxin is usually given for 7 to 14 days. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Clarithromycin will not treat a viral infection such as the flu or a common cold. Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication.
Store this medicine in the original container at room temperature, away from moisture, heat, and light. If your infection is treated with a combination of drugs, use all medications as directed by your doctor. Read the instructions provided with each medication. The goal in developing Biaxin Clarithromycin was to create a drug that would treat approximately the same conditions as Erythromycin with fewer gastrointestinal side effects. Ultimately, this goal was not achieved with medication, and the most common side effects are indigestion and diarrhea, which makes the drug similar to Erythromycin. Biaxin belongs to the class of macrolide antibiotics.
Biaxin fights bacteria in your body. Biaxin is used to treat many types of bacterial infections such as bronchitis, pneumonia, sinusitis, tonsillitis, skin infections, and bacterial stomach ulcers. Biaxin may be used for purposes other than those described in this manual. The antibiotic Biaxin is useful in the treatment of many common infections. It can especially be used for sinus, chronic bronchitis, or ear infections. It is also particularly effective against many forms of pharyngitis, and it is also useful for treating Legionella, Hemophilus infection, and bacteria that cause gonorrhea.
It should be noted that the choice of using any antibiotic depends in part on the type of bacteria, but also depends on other factors, such as medical conditions, age and medications that the patient takes. This means that the drug can be useful in the treatment of many diseases, but it is not the most suitable permanent choice. One of the reasons for choosing the antibiotic Biaxin, it may be the preferred choice because of its structure. It is more resistant to gastric juice. When taken orally, it survives better with the digestive process, which means more medication gets into the bloodstream.
Another reason for using this drug may be preferable, as it acts on bacteria. It inhibits the formation of bacterial proteins, which helps prevent the spread of bacteria. So it can be particularly effective in eliminating some bacterial forms. The actual amount of Biaxin needed to cure an infection varies. The specific dosage depends on the patient's age, type of infection and other factors, but most patients will take this medicine for 10-14 days. People need to complete their prescribed prescription completely or they will have the risk of re-infection. Who is prescribed Biaxin is clearly interested in the expected side effects. As already mentioned, one of the most common side effects is stomach upset, which can include abdominal pain, diarrhea, nausea or vomiting.
Patients are usually advised to take the medicine with food, as this can help reduce these symptoms. Although rare, some people who use this drug will develop other side effects, which may include rash, disorientation, headache, mood changes, hallucinations, dry mouth, and an unpleasant or metallic taste in the mouth. These symptoms should be given to the doctor, as well as any other symptoms that reduce urination or cause jaundice jaundice of the skin and eye proteins. Since Biaxin Clarithromycin is cleared through the liver, in very rare cases it may be associated with liver damage.
To avoid more serious side effects, patients should discuss with doctors what medications they are currently taking, including dietary supplements or herbs. They should also provide what medical conditions they have. Many people do not have negative reactions to this drug, and the antibiotic Biaxin can effectively treat them. In what cases should not take Biaxin? Before taking Biaxin, tell your doctor if you have kidney or liver disease. It may require a reduced dose and monitoring throughout the course of treatment, or withdrawal of the drug. Biaxin is classified as category C by the FDA in relation to pregnancy.
This means that it is not known whether the drug can adversely affect the fetus. If you are pregnant, do not take biaxin without consulting a doctor.